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Perinatal Practice Guidelines
Section 7
Chapter 120 - local anaesthetic toxicity
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Chapter 120 Severe local anaesthetic toxicity
Regimen for intravenous lipid emulsion
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Introduction
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Signs of severe toxicity
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Immediate management
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Management in cardiac arrest
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Management without cardiac arrest
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Follow-up
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References
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Last reviewed
Management in cardiac arrest
Commence cardiopulmonary resuscitation (CPR)
Manage arrhythmias, recognising that the arrhythmias may be very refractory to treatment
Consider the use of cardiopulmonary bypass if available
GIVE INTRAVENOUS INTRALIPID EMULSION
(
IV intralipid emulsion regimen flow chart
)
Follow regimen for intravenous lipid emulsion as above
Continue CPR throughout treatment with lipid emulsion
Recovery from LA-induced cardiac arrest may take >1 hour
Propofol is not a suitable substitute for lipid emulsion
Lidocaine should not be used as an anti-arrhythmic therapy
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Immediate management
| Page 5 of 9 |
Management without cardiac arrest